Jachowicz JW, Bing X, Pontabry J, Bošković A, Rando OJ, Torres-Padilla ME. LINE-1 activation after fertilization regulates global chromatin accessibility in the early mouse embryo. Nat Genet. 2017 Oct;49(10):1502-1510. doi: 10.1038/ng.3945. Epub 2017 Aug 28. PMID: 28846101.
Percharde M, Lin CJ, Yin Y, Guan J, Peixoto GA, Bulut-Karslioglu A, Biechele S, Huang B, Shen X, Ramalho-Santos M. A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity. Cell. 2018 Jul 12;174(2):391-405.e19. doi: 10.1016/j.cell.2018.05.043. Epub 2018 Jun 21. PMID: 29937225; PMCID: PMC6046266.
Meng, S. et al. Young LINE-1 transposon 5′ UTRs marked by elongation factor ELL3 function as enhancers to regulate naïve pluripotency in embryonic stem cells. Nat. Cell Biol. 25, 1319–1331 (2023).
Pal, D. et al. H4K16ac activates the transcription of transposable elements and contributes to their cis-regulatory function. Nat. Struct. Mol. Biol. 30, 935–947 (2023).
Li X et al. LINE-1 transcription activates long-range gene expression. Nature Genetics(2024)
Comments
评论暂时关闭
当前不公开历史评论正文;仅保留隐私安全统计和本地审核材料。新评论入口暂时关闭,避免在审核、反垃圾和通知邮件策略未确定前接收公开提交。